Characterization of deoxynivalenol-induced anorexia using mouse bioassay
نویسندگان
چکیده
منابع مشابه
High Sensitivity of Aged Mice to Deoxynivalenol (Vomitoxin)-Induced Anorexia Corresponds to Elevated Proinflammatory Cytokine and Satiety Hormone Responses
Deoxynivalenol (DON), a trichothecene mycotoxin that commonly contaminates cereal grains, is a public health concern because of its adverse effects on the gastrointestinal and immune systems. The objective of this study was to compare effects of DON on anorectic responses in aged (22 mos) and adult (3 mos) mice. Aged mice showed increased feed refusal with both acute i.p. (1 mg/kg and 5 mg/kg) ...
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ژورنال
عنوان ژورنال: Food and Chemical Toxicology
سال: 2011
ISSN: 0278-6915
DOI: 10.1016/j.fct.2011.05.004